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Atrial fibrillation increases the risk of stroke fivefold.
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Chamber fibrillation is A condition that occurs when there is a fault fashionable the electric action in the philia muscle, causing the heart to dead irregularly and stylish an uncoordinated way.
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How is dronedarone used in the treatment of AF?
Dronedarone is relatively a new drug which can lower the chances of hospitalization in patients having cardiovascular diseases especially those with paroxysmal or persistent atrial fibrillation (AF), having sinus rhythm (SR), or patients likely to be cardioverted[1].
Who is at risk for death from dronedarone?
Dronedarone may increase the risk of death in people who have severe heart failure. Tell your doctor if you have heart failure that is severe enough to cause shortness of breath while you are at rest, after a small amount of exercise, or after any physical activity.
What's the difference between amiodarone and dronedarone?
Dronedarone is a benzofuran containing heterocyclic compound and is a structural analog of amiodarone, but with slight structural modifications where the iodine group is replaced by a methane-sulfonyl group. The intention behind the replacement of iodine group is to reduce the risk of non-target organ adverse effects caused by amiodarone therapy.
What kind of properties does dronedarone have?
Like amiodarone, dronedarone has antiadrenergic (ie, beta blocking) properties and inhibits multiple transmembrane potassium currents, including the delayed rectifier current, the ultra-rapid delayed rectifier current, the inward rectifier current, and the transient outward current.
Last Update: Oct 2021
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